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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Jun 26;256(2):83–94. doi: 10.1016/j.taap.2011.06.018

Figure 5. Neutrophil infiltration in lungs of mice exposed to BNF prenatally and hyperoxia postnatally for 5 days (A).

Figure 5

The experiments were conducted as described in the legend to Figure 4, and except that the number of neutrophils were examined by immunohistochemistry, as described under Materials and Methods. The panels A, B, C, and D are defined in the legend to Figure 2. As shown in the figure, CO + O2 group showed much more number of neutrophils injury, compared to room air controls. The BNF + O2 group showed lesser number of neutrohils. Panel B shows the quantitative data of neutrophil infiltration at PND 1, 3, and 5. Data represent means ± SE of at least 3 mice from each group. a,and b depict statistically significant differences between each group versus the CO + air-breathing and BNF + O2, respectively, at P < 0.05.