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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Jun 26;256(2):83–94. doi: 10.1016/j.taap.2011.06.018

Figure 8. Effect of prenatal BNF and postnatal hyperoxia on pulmonary EROD (A), and CYP1A1 apoprotein expression (B).

Figure 8

The prenatal treatment of timed pregnant mice was conducted as described in legend to Figure 2, and fetuses (− 1 PND), and newborn mice were sacrificed at birth (0 PND), 1, 3, and 5 PND. Lungs were excised and microsomes were prepared in individual mice, and EROD activities were measured as described under Materials and Methods. Values represent means ± SE of at least 5 mice from each group. *, Statistically significant differences between each group versus the CO + air-breathing group at each time point at P < 0.05. CYP1A1 apoprotein expression in individual microsomes was determined by Western blotting, and the figure shows a representative Western blot.