Table 1.
IFN-γR−/− mice are susceptible to MPyV-induced tumorsa
| Mouse strain | Age at inoculation | Tumor incidence |
|---|---|---|
| C57BL/6 | Adult | 0/10 |
| Neonate | 0/13 | |
| IFN-γR−/− | Adult | 2/12 |
| Neonate | 9/9 |
Adult and newborn (<24 h old) C57BL/6 or IFN-γR−/− mice were inoculated s.c. with 1 × 106 PFU and 1 × 105 to 5 × 105 PFU of MPyV, respectively. Mice were necropsied when moribund or, if free of palpable tumors, at 6 months p.i.