Skip to main content
. 2011 Oct;85(19):9956–9963. doi: 10.1128/JVI.00097-11

Fig. 5.

Fig. 5.

Expression and antiviral restriction activity of M. fascicularis TRIMCyp. (A) Anti-HA immunoblot of CrFK and CrFK-derived TRIM5α- and TRIMCyp-expressing cell lines. (B) Restriction activity of CrFK and TRIMCyp-expressing cell lines against HIV-1 NL4-3. (C) Restriction activity against HIV-2 ROD. (D) Restriction activity against FIV. Controls are TRIM5α from M. mulatta (Mmu T5α) and TRIMCyp from M. nemestrina (Mne TC). Genotypes at amino acid positions 369 and 446 are shown as NE (N369/E446) or DK (D369/K446). Data shown are means ± standard deviations from three independent experiments using one representative dilution of virus (11 ng RT/well for HIV-1 and HIV-2 and 33 ng RT/well for FIV).