Figure 2. Measures for brain networks topological organization on the whole-brain level.

The mean and standard deviation of small-world statistical parameters from voxel-based networks at different correlation coefficient thresholds T. The parameters are: (A) shortest path length L, (B) clustering coefficient C, and (C) small-worldness . The horizontal dotted line in panel C indicates the significant difference of the small-worldness between the two groups among all of the thresholds. The most significant between-group difference was found at threshold T = 0.56. (D) The correlation between the global efficiency of CHUs' resting networks and the duration of heroin use while controlling for patients' age was at threshold T = 0.56.