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. 2011 Oct 18;6(10):e25589. doi: 10.1371/journal.pone.0025589

Figure 4. Tunicamycin induces ER stress in mucosal samples of healthy controls.

Figure 4

Stimulation of paired colonic and ileal samples of five healthy controls with the ER stress inducer tunicamycin revealed an increased expression of HSPA5 mRNA in both colonic and ileal tissue, with a more pronounced induction in the ileal mucosa (*Pā€Š=ā€Š0.048). Bars represent the fold induction of HSPA5 in treated samples relative to untreated samples.