Table 2. Selection intensity on 16 young fetal brain biased genes estimated by McDonald–Kreitman tests with Poisson random field [39].
RefSeq | Symbol | ds | ps | dn | pn | p | u | sd |
NM_133473 | ZNF431 | 5 | 0 | 11 | 0 | 0.00102 | 8.61813 | 4.83494 |
NM_182492 | DKFZp434O021 | 2 | 0 | 6 | 0 | 0.00814 | 7.68427 | 4.90936 |
NM_145298 | APOBEC3F | 0 | 1 | 11 | 2 | 0.0296 | 4.10728 | 3.49844 |
NM_018933 | PCDHB13 | 1 | 0 | 2 | 0 | 0.06178 | 6.39172 | 5.06886 |
NM_153608 | MGC17986 | 7 | 0 | 8 | 2 | 0.08628 | 3.18396 | 3.28736 |
NM_033213 | MGC12466 | 0 | 0 | 1 | 0 | 0.13642 | 5.36558 | 5.53891 |
NM_001700 | AZU1 | 1 | 3 | 1 | 0 | 0.13726 | 5.35647 | 5.58777 |
NM_024341 | ZNF557 | 2 | 0 | 3 | 1 | 0.16624 | 3.58025 | 4.13862 |
NM_020880 | ZNF530 | 4 | 0 | 3 | 1 | 0.16678 | 3.56122 | 4.0604 |
NM_178861 | ZNF183L1 | 1 | 2 | 2 | 1 | 0.27246 | 2.70492 | 4.17857 |
NM_005364 | MAGEA8 | 1 | 2 | 3 | 2 | 0.44028 | 1.00461 | 2.8012 |
NM_018260 | FLJ10891 | 0 | 1 | 1 | 1 | 0.53468 | 0.056067 | 5.14113 |
NM_033204 | ZNF101 | 5 | 0 | 3 | 4 | 0.8654 | −1.12073 | 1.47848 |
NM_207393 | IGFL3 | 0 | 1 | 0 | 1 | 0.907 | −6.04225 | 5.56359 |
NM_000200 | HTN3 | 0 | 1 | 0 | 2 | 0.98504 | −7.36289 | 4.7631 |
NM_015703 | CGI-96 | 2 | 1 | 0 | 3 | 0.99682 | −7.76714 | 4.63335 |
We discarded RefSeq sequences mapping to multiple Ensembl Genes. “ds,” “ps,” “dn,” and “pn” indicate the number of fixed synonymous sites, the number of polymorphic synonymous sites, the number of fixed non-synonymous sites, and the number of polymorphic non-synonymous sites, respective. “p” indicates whether the gene of interest have an selection intensity (λ = 2Ns) bigger than 0 (neutrality). “u” and “sd” show the estimation of mean and standard deviation of selection intensity. The five genes with p smaller than 0.1 were defined as positively selected genes.