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. 2011 Oct 18;6(10):e25717. doi: 10.1371/journal.pone.0025717

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Langford-Smith et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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At 4, 6 and 8 months of age 7–11 WT male (light grey bars), MPS IIIA male (dark grey bars), WT female (white bars) and MPS IIIA female (black bars) were placed on the elevated plus maze (A) and the behaviour was recorded for 10 minutes. After a 30 minute rest, the test was repeated. The results of the first test are presented as the mean of each measure with error bars representing the SEM. p values were calculated by 2 Way ANOVA. The following measures have been presented; the percentage of total entries that were into the open arm, the percentage of the path length in the open arm and the duration spent on the open arm at 4 (B), 6 (C) and 8 (D) months of age.