Table 2. Analysis of genotypes for K109R in case-control studies, according to different allelic modes of action.

Reference	Co-dominant: OR (95% CI)*	Co-dominant: p-value*	Dominant: OR (95% CI)**	Dominant: Chi2 (p-value)**	Recessive: OR (95% CI)**	Recessive: Chi2 (p-value)**
Caucasians
Chagnon 1999 [61]	0.82 (0.58–1.16)	0.253	0.94 (0.59–1.51)	0.07 (0.797)	0.38 (0.14–1.04)	4.70 (0.030)
Yiannakouris 2001 [10]	1.49 (0.62–3.61)	0.376	1.31 (0.45–3.83)	0.32 (0.574)	Not calculable	3.10 (0.079)
De Krom 2007 [63]	1.13 (0.78–1.62)	0.520	1.30 (0.77–2.18)	1.10 (0.294)	0.87 (0.34–2.23)	0.11 (0.739)
Masuo 2008 [16]	0.74 (0.37–1.48)	0.391	0.81 (0.34–1.93)	0.28 (0.599)	0.22 (0.01–7.46)	1.83 (0.177)
CoLaus men	0.91 (0.77–1.08)	0.298	0.91 (0.73–1.14)	0.67 (0.413)	0.81 (0.51–1.27)	0.95 (0.329)
CoLaus women	1.01 (0.86–1.18)	0.918	1.01 (0.82–1.23)	0.00 (0.959)	1.04 (0.67–1.60)	0.03 (0.872)
Overall	0.96 (0.87–1.07)	0.449	0.98 (0.86–1.12)	0.782	0.84 (0.63–1.12)	0.242
Asians
Qu 2007 [68]	1.04 (0.77–1.41)	0.800	0.97 (0.34–2.76)	0.00 (0.950)	1.06 (0.73–1.53)	0.10 (0.750)
Overall all populations	0.97 (0.88–1.07)	0.526	0.98 (0.86–1.12)	0.779	0.90 (0.72–1.13)	0.372

Odds ratios and 95% confidence intervals are given. Statistically significant results are shown in bold.

*Values from generalized linear model, overall results from meta-analysis, random model.

**Values from meta-analysis, random model.