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. 2011 Oct 18;6(10):e26135. doi: 10.1371/journal.pone.0026135

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Chan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Structures of compounds P61-A6 and P61-E7. (B) Treatment of P3-E5 with l-leucine methyl ester, O-benzotriazole-N,N,N′,N′-tetramethyluronium hexafluorophosphate (HBTU) and N,N-diisopropylethylamine (DIPEA) in dichloromethane provides P61-E7 in 95% isolated yield.