Skip to main content
. 2011 Oct 18;6(10):e26254. doi: 10.1371/journal.pone.0026254

Figure 8. Treatment of M. tuberculosis infected guinea pigs with NAC reduces pulmonary and extra-pulmonary granuloma necrosis.

Figure 8

The photomicrographs A, B, C and D represent lesion pathology in the lungs (A & B) and spleen (C & D) on day 30 in control (A & C) and NAC (B & D) treated animals. The arrows in A and C (controls) show a large core of necrosis and the arrowheads in B and C (NAC treated) point to granulomas with minimal to no necrosis. The photomicrographs E, F, G and H represent the lesion burden in the lungs (E & F) and spleen (G & H) on day 60 in control (E & G) and NAC (F & H) treated animals. The arrows in E and G (controls) show a large area of necrosis and the arrowheads in F and H (NAC treated) show the granulomas with smaller area of necrosis.