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. 2011 Oct 18;6(10):e26239. doi: 10.1371/journal.pone.0026239

Table 1. Influenza incidence rates according to subpopulation, diagnostic methods and vaccination status.

Subpopulation Diagnostic methods Vaccination status Number of seasons Number of Subjects I2 (P value) Incidence rate [95% confidence interval](n/100 population/season)
Families1 All infections Unvaccinated 1 62 NA 24.19 [15.05, 38.89]
Unknown 9 1,951 81% (<0.001) 13.56 [10.25, 17.94]
Symptomatic infections (serology) Unknown 1 96 NA 20.83 [13.75, 31.56]
Symptomatic infections (culture) Unknown 9 1,533 79% (<0.001) 4.96 [2.82, 8.71]
Working adults All infections Unvaccinated 4 4,373 93% (<0.001) 5.44 [3.01, 9.84]
Vaccinated 2 3,717 16% (0.28) 1.20 [0.86, 1.68]
Unknown 6 2,479 91% (<0.001) 9.13 [5.95, 14.01]
Symptomatic infections (serology) Unvaccinated 4 1,234 66% (0.03) 5.12 [3.08, 8.52]
Vaccinated 3 2,619 68% (0.04) 3.04 [1.79, 5.15]
Unknown 2 1,446 63% (0.10) 1.22 [0.48, 3.05]
Symptomatic infections (culture) Unvaccinated 8 9,393 90% (<0.001) 2.91 [1.78, 4.75]
Vaccinated 8 14,017 89% (<0.001) 1.35 [0.76, 2.41]
Symptomatic infections (PCR) Unvaccinated 1 325 NA 10.77 [7.76, 14.94]
Vaccinated 1 1,627 NA 5.16 [4.17, 6.40]
HCWs All infections Unvaccinated 10 2,273 66% (0.002) 18.69 [15.80, 22.11]
Vaccinated 8 3.026 73% (<0.001) 6.49 [4.63, 9.09]
Unknown 1 250 NA 11.20 [7.76, 16.17]
Symptomatic infections (serology) Unvaccinated 7 1,857 81% (<0.001) 7.54 [4.86, 11.70]
Vaccinated 7 3,092 76% (<0.001) 4.81 [3.23, 7.16]
Unknown 1 250 NA 8.00 [5.12, 12.49]
Symptomatic infections (culture) Unvaccinated 2 1,505 99% (<0.001) 6.24 [0.83, 46.88]
Vaccinated 1 698 NA 0.43 [0.11, 1.61]
Symptomatic infections (PCR) Unknown 1 422 NA 2.37 [1.22, 4.61]

Abbreviations: CI, confidence interval; NA, not applicable; HCWs, healthcare workers.

1

Working-age adults living in households with children.