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. 2011 Oct 18;6(10):e26288. doi: 10.1371/journal.pone.0026288

Figure 3. Age- and stroke-dependent expression of IL-6, TGFβ1 and IL-10.

Figure 3

IL-6 transcript expression significantly correlated with age; however, this correlation was not reflected in the expression of its protein. The post-ischemic IL-6 response was attenuated in aged brains (mRNA and protein). TGFβ1 mRNA significantly correlated with age. IL-10 mRNA tended to be elevated in aged brains. TGFβ1 transcript expression in the ischemic tissue increased continuously with reperfusion time at both ages. The up-regulation of TGFβ1 and IL-10 following ischemia tended to be attenuated in aged brains. Expression values are shown as mean ± SEM and ratios as geometric mean ± SEM. For details of the statistical analysis, see Figure 2's legend or the Materials and Methods section.