Table 3.

NS/S ratio comparison between de novo and rare inherited mutations in SCZ trios

	Cases					Controls
Class	Total Number	NS	S	NS/S	P value (de novo vs inherited)	Total Number	NS	S	NS/S	P value (de novo vs inherited)
de novo mutations	34	32	2	16		7	4	3	1.33
novel inherited mutations	14378	8867	5511	1.61	0.0002	6213	3825	2388	1.60	0.81
private inherited mutations	6727	4223	2504	1.69	0.0003	3079	1956	1123	1.74	0.73

S = Synonymous mutations

NS = Non-synonymous mutations