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. Author manuscript; available in PMC: 2012 Apr 24.
Published in final edited form as: AIDS. 2011 Apr 24;25(7):919–928. doi: 10.1097/QAD.0b013e328345889d

Table 2.

Prevalence of peripheral neuropathy and symptomatic peripheral neuropathy over time.

CD4>350 cells/µl
VL≤400 copies/ml
All patients
Week since
ART initiation
N Neuropathy
[% (95% CI)]
Symptomatic neuropathy
[% (95% CI)]
N Neuropathy
[% (95% CI)]
Symptomatic neuropathy
[% (95% CI)]
N Neuropathy
[% (95% CI)]
Symptomatic neuropathy
[% (95% CI)]
0 143 25.9 (18.9–33.9) 2.8 (0.8–7.0) 0 514 22.6 (19.0–26.4) 4.3 (2.7–6.4)
48 785 25.1 (22.1–28.3) 8.0 (6.2–10.2) 1276 29.1 (26.5–31.6) 10.0 (8.4–11.7) 1419 29.7 (27.3–32.1) 10.1 (8.6–11.8)
96 1069 29.2 (26.5–32.0) 7.7 (6.1–9.4) 1420 31.4 (29.1–33.9) 8.5 (7.1–10.1) 1598 31.5 (29.3–33.9) 8.7 (7.4–10.2)
144 1043 29.2 (26.3–31.9) 7.5 (6.0–9.2) 1293 31.9 (29.4–34.6) 8.5 (7.0–10.2) 1484 32.1 (29.8–34.6) 8.6 (7.2–10.2)
192 917 32.1 (29.5–35.2) 8.5 (6.8–10.5) 1083 32.6 (29.8–35.5) 9.3 (7.7–11.2) 1240 32.9 (30.3–35.6) 9.2 (7.6–10.9)
240 690 34.2 (30.7–37.9) 9.6 (7.5–12.0) 751 36.4 (32.9–39.9) 10.7 (8.5–13.1) 901 35.7 (32.6–39.0) 10.4 (8.5–12.6)
288 506 37.0 (32.7–41.3) 11.5 (8.8–14.6) 568 40.7 (36.6–44.8) 13.7 (11.0–16.8) 678 38.2 (34.5–42.0) 13.0 (10.5–15.7)
336 315 36.8 (31.5–42.4) 12.1 (8.7–16.2) 357 39.5 (34.4–44.8) 13.2 (9.8–17.1) 434 39.4 (34.8–44.2) 13.6 (10.5–17.2)
384 294 40.5 (34.8–46.3) 13.3 (9.6–17.7) 337 43.6 (38.3–49.1) 13.9 (10.4–18.1) 394 42.6 (37.7–47.7) 13.2 (10.0–16.9)
432 138 37.0 (28.9–45.6) 10.9 (6.2–17.3) 173 39.9 (32.5–47.6) 12.1 (7.7–18.0) 202 41.1 (34.2–48.2) 12.4 (8.2–17.7)

VL, viral load.