Figure 1. Resveratrol treatment increases survival and prevents body wasting in HS rats.

(A) Kaplan-Meier survival analyses for low salt (LS, N = 9), high salt (HS, N = 48) and high salt treated with resveratrol (HS-RSV, N = 14) groups showed decreased survival of HS-NT compared to LS groups (log-rank: χ² = 35.29, ***P<0.00001). Survival in HS-RSV rats was decreased compared to LS rats (log-rank: χ² = 4.75, *P = 0.041) but was significantly higher than HS-NT rats (log-rank: χ² = 39.78, ^$$$P = 0.0007). B. The HS-NT group showed continuous weight loss from the fifth week of salt intake compared to LS. Resveratrol completely prevented HF-induced weight loss. *P<0.05, **P<0.01, ***P<0.001 vs LS; ^$P<0.05, ^$$P<0.01, ^$$$P<0.001 vs HS-NT.