The crystal structure of Group VIII PLA2 (PAF-AH IB) α1 subunit (PDB entry 1WAB). Helixes are shown in light orange, β strands in purple and loops in light gray. The catalytic triad residues Ser-47, Asp-192 and His-195 are shown in red sticks. The specific pocket is comprised of residues Leu-48, Thr-103 and Leu-194, which defines the enzyme substrate specificity, are shown in blue sticks.