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. Author manuscript; available in PMC: 2012 Oct 12.
Published in final edited form as: Chem Rev. 2011 Sep 12;111(10):6130–6185. doi: 10.1021/cr200085w

Table 16.

Group IVA PLA2 Inhibition by Fatty Acid Trifluoromethyl Ketones

R-COCF3 XI(50)
DOPM/GLU mixed-micelles natural membrane
20:4 0.0050±0.001 0.036±0.006 0.05±0.02
11, 14, 17–20:3 0.0085±0.002 0.020±0.002 0.10±0.03
16:1 0.0083±0.001 0.010±0.003 0.07±0.02
16:0 0.025±0.002 0.022±0.006 0.20±0.03