Table 21.
Group VI Calcium Independent Phospholipase A2s (iPLA2)
| Subgroup | Alternative name |
Sources | Residues /Molecular Mass |
Domain | Alt Splice |
Activity | Post Translational Modification |
Human chromosome |
Swiss- Prot |
|---|---|---|---|---|---|---|---|---|---|
| GVIA | iPLA2β PNPLA9 |
Human/ Murine |
750/85 kDa 806/87 kDa |
7–8 Ankyrin Repeats α/ β hydrolase (Patatin like Lipase) |
5 | PLA2, Lyso-PLA transacylase acyl-CoA thioesterase |
22q13. 1 |
O60733 | |
| GVIB | iPLA2γ PNPLA8 |
Human/ Murine |
782/90 kDa | α/ β hydrolase (Patatin like Lipase) |
2 | PLA1, PLA2, Lyso-PLA transacylase |
7q31 | Q9NP8 0 |
|
| GVIC | iPLA2δ PNPLA6 NTE |
Human/ Murine |
1366/146 kDa |
3 cNMP α/ β hydrolase (Patatin like Lipase) |
3 | PLA2 Lyso-PLA |
Phosphorylatio n (5) |
19p13. 3-13.2 |
Q8IY17 |
| GVID | iPLA2ε PNPLA3 ADPN |
Human | 481/52 kDa | α/ β hydrolase (Patatin like Lipase) |
2 | PLA2, TG hydrolase, transacylase |
22q13. 31 |
Q9NST 1 |
|
| GVIE | iPLA2ζ PNPLA2 ATGL |
Human | 504/55 kDa | α/ β hydrolase (Patatin like Lipase) |
2 | PLA2 TG hydrolase, transacylase |
Phosphorylatio n (1) |
11p15. 5 |
Q96AD 5 |
| GVIF | iPLA2η PNPLA4 GS2 |
Human | 253/27 kDa | α/ β hydrolase (Patatin like Lipase) |
PLA2, TG hydrolase, retinylester hydrolase acylglycerol and retinol transacylase |
Phosphorylatio n (1) |
xp22.3 | P41247 |