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Comparison of Group VIA, Group IVA and Group V PLA2 Inhibition by Polyfluoroalkyl Ketonesa
| Compound | GVIA PLA2 | GIVA PLA2 | GV sPLA2 |
|---|---|---|---|
| 96 | >90% 0.0073 ± 0.0007 |
N.D. | 28 ± 1% |
| 97 | >90% 0.0169 ± 0.021 |
>90% 0.0098 ± 0.0006 |
86 ± 2 % |
Average percent inhibition at 0.091 mol fraction and XI(50) and standard error (n = 3) are reported for each compound. N.D. signifies compounds with less than 25% inhibition (or no detectable inhibition).
