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. Author manuscript; available in PMC: 2012 Oct 12.
Published in final edited form as: Chem Rev. 2011 Sep 12;111(10):6130–6185. doi: 10.1021/cr200085w

Table 24.

Comparison of Group VIA, Group IVA and Group V PLA2 Inhibition by Polyfluoroalkyl Ketonesa

Compound GVIA PLA2
XI(50)		 GIVA PLA2
% Inhibition		 GV sPLA2
% Inhibition
98 0.0002 ±0.0000 80.8 ± 1.5 % 36.8 ± 7.9 %
99 0.0010 ± 0.0001 55.8 ± 2.1 % 46.3 ±10.0 %
a

Average percent inhibition at 0.091 mol fraction and standard error (n = 3) are reported for each compound or XI(50) and standard error (n = 3) for those with >90% inhibition.