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. Author manuscript; available in PMC: 2012 Oct 12.
Published in final edited form as: Chem Rev. 2011 Sep 12;111(10):6130–6185. doi: 10.1021/cr200085w

Table 25.

Comparison of Group VIA, Group IVA and Group V PLA2 Inhibition by 2-Oxoamidesa

Compound GVIA PLA2
XI(50)
GIVA PLA2
% Inhibition
GV PLA2
% Inhibition
100 0.011 ± 0.001 72 59
101 0.017 ± 0.002 52 81
a

Average percent inhibition at 0.091 mol fraction are reported for each compound or XI(50) and standard error (n = 3) for those with >90% inhibition.