Figure 4. Regulation of growth signaling by protein phosphorylation and metabolism.
Modes of mammalian signal transduction. Examples of modifications, enzymes, substrates and the primary form of regulation are shown.
Abbreviations: OGT – O-linked N-acetylglucosamine transferase, GLCNAC – N-acetylglucosamine, PARP – Poly (ADP-ribose) polymerase, SAM – S-adenosylmethionine.