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Histology Grading Scale Used to Grade Degree of Intestinal Injury in Resected Terminal Ileum Specimens from Experimental NEC and Control Pups
| Grade | Histologic findings |
|---|---|
| 1 | Mild submucosal and/or lamina propria separation |
| 2 | Moderate submucosal and/or lamina propria separation and/or edema in submucosa and/or muscular layers |
| 3 | Severe submucosal and/or lamina propria separation and/or edema in submucosal and muscular layers and regional villous sloughing |
| 4 | Necrosis, loss of villi |
