TABLE 2.
Weight Gain (%) and Relative Organ Weights (%) under Each Experiment Condition and Significance of Various Comparisons
| Treatment | Dietary Se level |
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| Low (0.02 ppm) | Adequate (0.2 ppm) | Supplemental (2 ppm) | 2-Way ANOVA | ||
| Growth (%) | Corn oil | 21.1 ± 1.2 | 21.1 ± 1.7 | 21.4 ± 1.7 | n/a |
| 0.2 μmol/kg PCB 126 | 19.3 ± 1.4 | 16.1 ± 1.9 | 16.9 ± 2.0 | * | |
| 1 μmol/kg PCB 126 | 16.6 ± 2.1 | 15.7 ± 2.2 | 14.1 ± 1.2* | * | |
| 5 μmol/kg PCB 126 | −5.1 ± 2.5* | −4.2 ± 1.9* | −0.6 ± 1.1* | * | |
| 2-Way ANOVA | — | n/a | — | ||
| Relative liver weight (%) | Corn oil | 3.86 ± 0.07 | 4.11 ± 0.06 | 4.36 ± 0.10 | n/a |
| 0.2 μmol/kg PCB 126 | 5.00 ± 0.19* | 5.57 ± 0.17* | 4.84 ± 0.17# | * | |
| 1 μmol/kg PCB 126 | 6.02 ± 0.10* | 6.27 ± 0.17* | 6.15 ± 0.17* | * | |
| 5 μmol/kg PCB 126 | 6.91 ± 0.43* | 7.01 ± 0.31* | 7.52 ± 0.14* | * | |
| 2-Way ANOVA | — | n/a | — | ||
| Relative lung | Corn oil | 0.459 ± 0.012 | 0.464 ± 0.009 | 0.493 ± 0.018 | n/a |
| Weight (%) | 0.2 μmol/kg PCB 126 | 0.526 ± 0.015 | 0.573 ± 0.023* | 0.514 ± 0.022 | * |
| 1 μmol/kg PCB 126 | 0.622 ± 0.031* | 0.557 ± 0.024* | 0.611 ± 0.038 | * | |
| 5 μmol/kg PCB 126 | 0.596 ± 0.026* | 0.653 ± 0.027* | 0.604 ± 0.040 | * | |
| 2-Way ANOVA | — | n/a | — | ||
| Relative | Corn oil | 0.228 ± 0.012 | 0.197 ± 0.012 | 0.213 ± 0.006 | n/a |
| Thymus | 0.2 μmol/kg PCB 126 | 0.161 ± 0.003* | 0.151 ± 0.009* | 0.171 ± 0.012* | * |
| Weight (%) | 1 μmol/kg PCB 126 | 0.101 ± 0.008* | 0.089 ± 0.006* | 0.084 ± 0.004* | * |
| 5 μmol/kg PCB 126 | 0.057 ± 0.004* | 0.046 ± 0.002* | 0.038 ± 0.004* | * | |
| 2-Way ANOVA | # | n/a | — | ||
Note. Results are expressed as mean ± SEM. Each group contained four to six animals. One-way ANOVA was used to examine statistically significant differences (p < 0.05) between each PCB 126 level and the corn oil treatment (indicated by “*” if significant) and between low or supplemental and the adequate dietary Se level (indicated by “#” if significant). Significance for each factor based on two-way ANOVA is indicated in the “2-way ANOVA” rows by “#” for Se level and the “2-way ANOVA” column by “*” for PCB 126 level. All p values have been adjusted for multiple testing using Dunnett’s test. n/a, not applicable.