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. 2011 Aug 24;124(1):202–214. doi: 10.1093/toxsci/kfr215

TABLE 2.

Weight Gain (%) and Relative Organ Weights (%) under Each Experiment Condition and Significance of Various Comparisons

Treatment Dietary Se level
Low (0.02 ppm) Adequate (0.2 ppm) Supplemental (2 ppm) 2-Way ANOVA
Growth (%) Corn oil 21.1 ± 1.2 21.1 ± 1.7 21.4 ± 1.7 n/a
0.2 μmol/kg PCB 126 19.3 ± 1.4 16.1 ± 1.9 16.9 ± 2.0 *
1 μmol/kg PCB 126 16.6 ± 2.1 15.7 ± 2.2 14.1 ± 1.2* *
5 μmol/kg PCB 126 −5.1 ± 2.5* −4.2 ± 1.9* −0.6 ± 1.1* *
2-Way ANOVA n/a
Relative liver weight (%) Corn oil 3.86 ± 0.07 4.11 ± 0.06 4.36 ± 0.10 n/a
0.2 μmol/kg PCB 126 5.00 ± 0.19* 5.57 ± 0.17* 4.84 ± 0.17# *
1 μmol/kg PCB 126 6.02 ± 0.10* 6.27 ± 0.17* 6.15 ± 0.17* *
5 μmol/kg PCB 126 6.91 ± 0.43* 7.01 ± 0.31* 7.52 ± 0.14* *
2-Way ANOVA n/a
Relative lung Corn oil 0.459 ± 0.012 0.464 ± 0.009 0.493 ± 0.018 n/a
Weight (%) 0.2 μmol/kg PCB 126 0.526 ± 0.015 0.573 ± 0.023* 0.514 ± 0.022 *
1 μmol/kg PCB 126 0.622 ± 0.031* 0.557 ± 0.024* 0.611 ± 0.038 *
5 μmol/kg PCB 126 0.596 ± 0.026* 0.653 ± 0.027* 0.604 ± 0.040 *
2-Way ANOVA n/a
Relative Corn oil 0.228 ± 0.012 0.197 ± 0.012 0.213 ± 0.006 n/a
Thymus 0.2 μmol/kg PCB 126 0.161 ± 0.003* 0.151 ± 0.009* 0.171 ± 0.012* *
Weight (%) 1 μmol/kg PCB 126 0.101 ± 0.008* 0.089 ± 0.006* 0.084 ± 0.004* *
5 μmol/kg PCB 126 0.057 ± 0.004* 0.046 ± 0.002* 0.038 ± 0.004* *
2-Way ANOVA # n/a

Note. Results are expressed as mean ± SEM. Each group contained four to six animals. One-way ANOVA was used to examine statistically significant differences (p < 0.05) between each PCB 126 level and the corn oil treatment (indicated by “*” if significant) and between low or supplemental and the adequate dietary Se level (indicated by “#” if significant). Significance for each factor based on two-way ANOVA is indicated in the “2-way ANOVA” rows by “#” for Se level and the “2-way ANOVA” column by “*” for PCB 126 level. All p values have been adjusted for multiple testing using Dunnett’s test. n/a, not applicable.