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Lrig1 expression is associated with ERα status in human breast cancer. LRIG1 gene expression profiles and ERα phenotypic data of 363 breast carcinomas were obtained from two publicly available breast cancer microarray data sets. Correlation of Lrig1expression levels with ERα status of breast cancer specimens. Lrig1 is significantly overexpressed in the ER-positive tumors versus the ER-negative tumors using the t-test (p=0.0001). Left panel, Chin study. Right panel, Ivshina study.
