Table 1.
General features of Mycoplasma haemofelis strain Ohio2 genome compared to members of pneumoniae, hominis and mycoides phylogenetic groups of Mycoplasmas.
| Pneumoniae group | Hominis group | Mycoides group | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Feature | M. haemofelis | M. suis | M. pneumoniae | M. gallisepticum | M. genitalium | M. penetrans | M. hominis | M. hyopneumoniae | M. synoviae | M. pulmonis | M. mycoides |
| Genome size (bp) | 1 155 937 | 742 431 | 816 394 | 1 012 800 | 580 076 | 1 358 633 | 665 445 | 897 405 | 799 476 | 963 879 | 1 211 703 |
| G + C content (%) | 38.8 | 31.1 | 40 | 31 | 31.7 | 25.7 | 27.1 | 28 | 28 | 26.6 | 24 |
| Total of genes | 1584 | 883 | 733 | 817 | 524 | 1069 | 577 | 701 | 715 | 815 | 1053 |
| Coding sequences | 1549 | 844 | 689 | 763 | 475 | 1037 | 523 | 657 | 659 | 782 | 1017 |
| Pseudogenes | 22 | 4 | 0 | 14 | 6 | 0 | 14 | 11 | 15 | 0 | 0 |
| Gene density (%) | 94.2 | 89.9 | 88.7 | 91 | 90 | 88 | 89.8 | 88 | 91 | 91.4 | 83 |
| Average gene length (bp) | 693 | 783 | 1011 | 1,206 | 1,040 | NRa | 1,107 | 1,178 | 1,058 | 1,115 | 982 |
| CDS with predicted function | 299 (19.3%) |
293 (34.7%) |
333 (48.3%) |
469 (61.46%) |
323 (68%) |
585 (56.4%) |
345 (65.9%) | 412 (62.7%) |
464 (70.4%) |
486 (62.1%) |
581 (57.1%) |
| No. of tRNAs | 31 | 32 | 37 | 32 | 36 | 29 | 33 | 30 | 34 | 29 | 30 |
| No. of rRNAs | |||||||||||
| 16S | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 2 |
| 23S | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 2 |
| 5S | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 3 | 2 | 2 |
| Genes in paralogous families | 1103 (71.2%) |
361 (42.8%) |
132 (19.1%) |
110 (14.4%) |
25 (5.2%) |
245 (23.6%) |
38 (7.2%) |
106 (16.1%) |
121 (18.3%) |
101 (12.9%) |
266 (26.1%) |
Data was obtained from the GenBank database using the following accession numbers: M. haemofelis (CP002808), M. suis (CP002525), M. pneumoniae (U00089), M. gallisepticum (AE015450), M. genitalium (L43967), M. penetrans (BA000026), M. hominis (FP236530), M. hyopneumoniae (AE017243), M. synoviae (AE017245), M. pulmonis (AL445566), M. mycoides (BX293980). Paralogous gene families were assigned using BLASTclust, with 30% sequence identity and 70% covered length thresholds.
a NR, not reported.