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. 2011 Oct 16;3(10):195–200. doi: 10.4253/wjge.v3.i10.195

Table 2.

Indications for esophagogastroduodenoscopy and diagnostic yield according to the American Society for Gastrointestinal Endoscopy guidelines n (%)

ASGE Indication Frequency Relevant lesions (%) P
Appropriate indication 315 (82.7) 36.6
Upper abdominal symptoms1 108 (28.3) 21.3 0.001
Esophageal reflux symptoms that are persistent or recurrent despite appropriate therapy 46 (12.1) 39.1 0.412
Portal hypertension evaluation 30 (7.9) 80.0 < 0.0001
Follow-up of gastric ulcer 24 (6.3) 33.3 1.0
Iron deficiency anemia 23 (6.0) 13.0 0.018
Endoscopic treatment 18 (4.7) 77.8 < 0.0001
Dysphagia or odynophagia 16 (4.1) 62.5 0.027
Surveillance for malignancy in patients with Barrett’s esophagus 11 (2.9) 90.9 < 0.0001
Persistent vomiting of unknown cause 11 (2.9) 18.2 0.346
Active or recent GI bleeding 10 (2.6) 30.0 1.0
For confirmation and specific histologic diagnosis of radiologically demonstrated lesions 8 (2.1) 50.0 0.451
Sampling of tissue or fluid 7 (1.8) 14.3 0.236
Others 24 (6.2) 25.0 0.523
Uncertain indication 22 (5.8) 36.4
Anemia not otherwise characterized 22 (5.8) 36.4 1.0
Inappropriate indication 44 (11.5) 11.4
Surveillance for malignancy in patients with chronic gastritis 11 (2.9) 0 < 0.0001
Surveillance for malignancy in patients with prior gastric operation 10 (2.6) 25.0 0.758
Follow-up of duodenal ulcer 8 (2.1) 30.0 1.0
Others 15 (3.8) 0 < 0.0001
1

Upper abdominal symptoms persistent, despite therapy, associated with symptoms or signs suggesting serious organic disease or occurring in patients > 45 years old. ASGE: American Society for Gastrointestinal Endoscopy; GI: Gastrointestinal.