Table 1.
Average relative error (ARE) in model fitting to cell counts simulated in Scenario 1.
Model | Parameter range | ARE(%) of time to division of gen. 0 | ARE(%) of time to division of gen. ≥1 | ARE(%) of time to death of gen. 0 | ARE(%) of time to death of gen. ≥1 |
---|---|---|---|---|---|
Branching Process (2.9) | ±5% | 7.73 | 4.26 | 0.56 | 21.9 |
±10% | 9.06 | 5.58 | 0.69 | 27.6 | |
±20% | 7.76 | 6.93 | 0.67 | 39.7 | |
±30% | 7.66 | 7.71 | 0.59 | 49.8 | |
±50% | 7.52 | 18.2 | 1.03 | 84.6 | |
overall | 7.95 | 8.53 | 0.71 | 44.7 | |
| |||||
Branching Process (2.10) | ±5% | 8.20 | 18.6 | 24.4 | 131 |
±10% | 7.75 | 23.0 | 24.6 | 101 | |
±20% | 9.42 | 34.9 | 24.1 | 195 | |
±30% | 12.1 | 30.3 | 23.4 | 194 | |
±50% | 22.7 | 64.1 | 21.3 | 206 | |
overall | 12.3 | 34.2 | 23.5 | 166 | |
| |||||
Cyton | ±5% | 6.24 | 26.4 | 29.0 | 59.2 |
±10% | 8.59 | 26.2 | 25.5 | 64.9 | |
±20% | 12.9 | 29.7 | 19.9 | 79.8 | |
±30% | 19.5 | 27.6 | 19.0 | 80.0 | |
±50% | 24.2 | 42.2 | 27.1 | 103 | |
overall | 14.3 | 30.4 | 24.1 | 77.4 | |
| |||||
Simple ODE | ±5% | 527 | 406 | 1.92 × 1010 | 5.65 × 1011 |
±10% | 556 | 427 | 1.00 × 1010 | 3.76 × 1011 | |
±20% | 629 | 485 | 2.44 × 1010 | 5.62 × 1011 | |
±30% | 694 | 474 | 2.07 × 1010 | 2.40 × 1011 | |
±50% | 899 | 640 | 5.27 × 1010 | 1.03 × 1012 | |
overall | 661 | 486 | 2.54 × 1010 | 9.86 × 1011 | |
| |||||
Smith-Martin | ±5% | 321 | 155 | 1.68 × 1016 | 4.82 × 1015 |
±10% | 297 | 168 | 1.30 × 1016 | 1.38 × 1015 | |
±20% | 315 | 178 | 5.52 × 1016 | 1.04 × 1015 | |
±30% | 352 | 171 | 1.37 × 1016 | 2.25 × 1015 | |
±50% | 406 | 227 | 7.34 × 1016 | 7.22 × 1015 | |
overall | 338 | 180 | 3.44 × 1016 | 3.34 × 1015 |