Table 4.
Major clinical characteristics of combined derivation and validation cohorts.1
| Subclass A | Subclass B | Subclass C | p value | |
|---|---|---|---|---|
| No. of patients | 55 | 69 | 56 | -- |
| Median age in years (IQR)2 | 0.7 (0.3–2.7) | 5.2 (1.9–7.3) | 2.2 (1.2–2.7) | <0.001 |
| No. of males/females | 39/16 | 33/36 | 37/19 | 0.020 |
| No. of deaths (%) | 16 (29)3 | 7 (10) | 7 (12) | 0.012 |
| Max. # of organ failures (IQR) | 3 (2–4) | 2 (2–3) | 2 (2–2) | <0.001 |
| Median PRISM score (IQR) | 19 (13–27) | 11 (10–15) | 12 (9–16) | <0.001 |
| Median PICU free days (IQR) | 11 (0–18) | 22 (17–24) | 19 (16–24) | 0.002 |
1
Continuous variables are analyzed as 3 group comparisons using ANOVA on Ranks and 2 degrees of freedom. Proportions are analyzed as 3 group comparisons using a 2 by 3 contingency table and Chi-square with 2 degrees of freedom.
2
Interquartile range (IQR).
3
Odds ratio for mortality vs. Subclass B: 3.6 (1.4– 9.6), p = 0.007; vs. Subclass C: 2.9 (1.1–7.7), p = 0.03.