Skip to main content
. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: J Cell Biochem. 2011 Nov;112(11):3289–3299. doi: 10.1002/jcb.23255

Figure 8.

Figure 8

DN-Cdc42 as well as PAK1, but not DN-PAK cotransfected with recombinant CIB1 attenuated CIB1-induced cell migration. A&B: Quantitative analysis of transwell migration assay of mock or CIB1-overexpressing cells in the presence or absence of (A) DN-Cdc42, or (B) constitutively active (PAK1) or DN-PAK1. Transfected cells were allowed to migrate on Fn for 5 h. Triplicate inserts were used for each treatment. Ten random views of each insert were counted. Data is expressed as percent control. Number of mock cells migrating across the membrane was considered 100 percent. Each experiment was repeated independently three times. *P<0.05 vs untreated CIB1 overexpressed.