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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Neurobiol Aging. 2011 Jun 17;33(7):1487.e1–1487.e13. doi: 10.1016/j.neurobiolaging.2011.05.004

Fig. 4.

Fig. 4

RT-PCR results showing expression of key genes involved in the intracrine conversion of DHEA/S to 17β-estradiol, within the rhesus macaque amygdala, hippocampus, arcuate nucleus of the medial basal hypothalamus (MBH), and prefrontal (PF) cortex; mRNA from the adrenal gland was used as the positive control for all reactions except 17BHSD3, which used mRNA from the testis. Brain areas shown are from a representative ovariectomized female rhesus macaque. The bands in the gels corresponded to the predicted size of 200–500 nucleotides. The data suggest that DHEA and DHEAS are major precursors in primate neurosteroidogenesis.