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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: J Thorac Oncol. 2011 Nov;6(11):1784–1792. doi: 10.1097/JTO.0b013e31822adfb0

Figure 2. Effect of rapamycin, 17-AAG and LY 294002 on migration and invasion during TGF-β induced EMT.

Figure 2

A549 or H358 cells were serum starved for 24 h, stimulated with TGF-ß (5 ng/ml) in the presence or absence of inhibitors at indicated concentrations. After 72 h cells were trypsinized and plated in uncoated or matrigel coated transwell chambers to assess cellular migration and invasion respectively. Error bars represent the standard deviation (SD) from three independent replicates. (*) denotes statistically significant (P<0.05) difference when compared to TGF-β treated cells.