Table 5.

Top 25 canonical pathways

Canonical pathways
CCK/gastrin-mediated signalling
Synaptic long-term potentiation
Semaphorin signalling in neurons
Neuropathic pain signalling in dorsal horn neurons
Chemokine signalling
GNRH signalling
RhoA signalling
Renin-angiotensin signalling
NFAT in cardiac hypertrophy
Glutamate receptor signalling
Axonal guidance signalling
CDK5 signalling
Integrin signalling
CXCR4 signalling
Ephrin receptor signalling
Molecular mechanisms of cancer
Melatonin signalling
Thrombin signalling
CREB signalling in neurons
Protein kinase A signalling
IGF-1 signalling
Regulation of actin-based motility by rho
Calcium signalling
ERK/MAPK signalling
Corticotropin-releasing hormone signalling

CREB, cAMP response element-binding; ERK, extracellular receptor kinase; GNRH, gonadotropin-releasing hormone; IGF-1, insulin-like growth factor 1; MAPK, mitogen-activated protein kinase; NFAT, nuclear factor of activated T-cells.