Table 6.

Top 10 canonical pathways

Pharmacoresistant epilepsy	Alzheimer's disease
CCK/gastrin-mediated signalling	Protein ubiquitination pathway
Synaptic long-term potentiation	Mitochondrial dysfunction
Semaphorin signalling in neurons	Regulation of eIF4 and p70S6K signalling
Neuropathic pain signalling in dorsal horn neurons	eIF2 signalling
Chemokine signalling	Oxidative phosphorylation
GNRH signalling	Purine metabolism
RhoA signalling	Breast cancer regulation by stathmin 1
Renin-angiotensin signalling	NRF2-mediated oxidative stress response
Role of NFAT in cardiac hypertrophy	Huntington's disease signalling
Glutamate receptor signalling	Oestrogen receptor signalling