Table 4.
Hazard ratios for the significant association between ADIPOR2 SNPs and the development of CVD during follow-up of median 10.2 years
| HR (95% CI), p/qa | HR, 95% CI, p/qb | ||
|---|---|---|---|
| rs10848554 | GG (358) | 1 | 1 |
| GC (102) | 1.510 (0.957-2.382), 0.076/0.110 | 1.565 (1.004-2.440), 0.048/0.095 | |
| CC (7) | 2.919 (0.697-12.23), 0.143/0.150 | ||
| rs11061937 | TT (207) | 1 | 1 |
| TC (206) | 0.568 (0.364-0.885), 0.012/0.095 | 0.595 (0.395-0.896), 0.013/0.095 | |
| CC (54) | 0.701 (0.353-1.390), 0.309/0.238 | ||
| rs1058322 | CC (218) | 1 | 1 |
| CT (201) | 1.601 (1.021-2.509), 0.040/0.095 | 1.711 (1.114-2.627), 0.014/0.095 | |
| TT (48) | 2.300 (1.194-4.433), 0.013/0.095 | ||
| rs16928751 | GG (364) | 1 | 1 |
| GA (99) | 1.677 (1.051-2.674), 0.030/0.095 | 1.756 (1.114-2.766), 0.015/0.095 | |
| AA (4) | 4.425 (1.042-18.79), 0.044/0.095 | ||
All analyses were adjusted for age, sex, baseline waist circumference, baseline 2-h plasma glucose and study group; Correction for multiple hypothesis testing in single SNP analyses was performed by using FDR, denoted as q-value; aAdditive inheritance model for single SNP analyses; bDominant inheritance model for single SNP analyses.