Table 5.
Hazard ratios for the significant association between ADIPOR2 SNPs and the development of T2DM during follow-up of median 7 years
| HR (95% CI), p/qa | HR (95% CI), p/qb | ||
|---|---|---|---|
| rs11061946 | CC (428) | 1 | 1 |
| CT (49) | 0.706 (0.412- 1.211), 0.206/0.517 | 0.872 (0.536- 1.417), 0.579/0.596 | |
| TT (5) | 5.538 (2.014- 15.226), 0.001/0.369 | ||
| rs11061973 | GG (401) | 1 | 1 |
| GA (76) | 0.951 (0.636- 1.423), 0.808/0.657 | 1.061 (0.724- 1.557), 0.761/0.657 | |
| AA (5) | 5.683 (2.066- 15.636), 0.001/0.369 | ||
All analyses were adjusted for CVD at baseline, age, sex, baseline waist circumference, baseline total to HDL cholesterol ratio, smoking status, systolic blood pressure and study group; Correction for multiple hypothesis testing in single SNP analyses was performed by using FDR, denoted as q-value; aAdditive inheritance model for single SNP analyses; bDominant inheritance model for single SNP analyses.