Table 2.
Functional classification of genes the expression of which in TM4 cells was modulated by NP
| Function | No. of genes | |
|---|---|---|
| 3 h | 24 h | |
| Transport | 77 | 278 |
| Signal transduction | 102 | 250 |
| Transcription | 73 | 169 |
| Cell differentiation | 38 | 119 |
| Cell cycle | 28 | 100 |
| Response to stress | 38 | 78 |
| Lipid metabolism | 20 | 75 |
| Apoptosis | 28 | 70 |
| Cell adhesion | 23 | 70 |
| Behavior | 11 | 59* |
| Cell proliferation | 19 | 54 |
| Protein biosynthesis | 18 | 54 |
| Immune response | 20 | 42 |
| Angiogenesis | 10 | 29 |
| Homeostasis | 7 | 28 |
| Growth | 6 | 26 |
| Cell-cell signaling | 7 | 19 |
| Gametogenesis | 3 | 17* |
| Spermatogenesis | 1 | 12* |
| Inflammatory response | 6 | 10 |
| Total number of genes | 535 | 1,559 |
*Number of genes hit into the categories remarkably increased (over 5-fold) at 24 h comparing to at 3 h