Table 2.
Concentration of circulating creatinine, pyrimidine (β-pseudouridine and uridine), oxypurines (hypoxanthine, xanthine and uric acid) malondialdehyde (MDA), nitrite and nitrate (NO2 + NO3), and ascorbic acid determined by HPLC in serum samples of healthy controls and MS patients.
| Controls (n = 163) | MS patients (n = 170) | |
|---|---|---|
| Creatinine | 56.87 ± 17.98 | 71.10 ± 19.27a |
| Uracile | 1.97 ± 0.90 | 2.11 ± 1.04 |
| β-pseudouridine | 3.03 ± 1.24 | 4.67 ± 1.71a |
| Uridine | 4.83 ± 2.19 | 7.20 ± 1.82a |
| Hypoxanthine | 4.19 ± 1.58 | 12.30 ± 4.84a |
| Xanthine | 1.44 ± 0.96 | 4.03 ± 2.20a |
| Uric acid | 258.08 ± 50.39 | 299.88 ± 70.17a |
| MDA | 0.005 ± 0.004 | 0.84 ± 0.54a |
| NO2 + NO3 | 69.06 ± 29.04 | 107.94 ± 43.87a |
| Ascorbic acid | 57.52 ± 14.81 | 37.36 ± 10.95a |
Values are means ± standard deviations and are expressed in μmol/L serum.
asignificantly different from controls (P < .001).