Table 1.
Prenatal Treatment | Preventive Treatment | PND 34 (Before First Injection) | PND 40 (During Injection) | PND 47 (Before Last Injection) |
Mean ± SEM Body Weight (g) | ||||
Saline | Vehicle | 131.5 ± 2.9 | 181.4 ± 4.7 | 234.5 ± 4.9 |
RIS-low | 135.6 ± 3.0 | 182.3 ± 3.4 | 235.6 ± 3.0 | |
RIS-high | 133.9 ± 4.8 | 179.5 ± 4.7 | 229.9 ± 5.5 | |
Poly I:C | Vehicle | 145.9 ± 5.0 | 197.4 ± 5.8 | 252.7 ± 6.4 |
RIS-low | 127.4 ± 2.3 | 175.2 ± 3.4 | 212.6 ± 7.0 | |
RIS-high | 137.2 ± 5.0 | 185.1 ± 5.9 | 234.5 ± 6.9 |
Note: Body weight (g) of the offspring of saline (CON)- or poly I:C–injected dams treated with vehicle, 0.045 mg/kg RIS (RIS-low), or 1.2 mg/kg RIS (RIS-high) on PND 34 (before commencement of preventive treatment), PND 40, and PND 47 (termination of treatment). All values are means ± standard error of the mean. ANOVA yielded no significant effects for prenatal or preventive treatment.