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Mean thermode temperature by series. Thermode temperatures (ordinate) averaged across 3 sessions of response-dependent stimulation that maintained an average eVAS rating of 35 for pain intensity. Thermode temperatures are shown for 4 sequential series of 25 stimuli with durations of 1.0 second (series 1 and 3) and 0.8 seconds (series 2 and 4). Hyperalgesia for cutaneous thermal stimulation was revealed by lower thermode temperatures within each series.
