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. Author manuscript; available in PMC: 2011 Oct 19.
Published in final edited form as: Mol Divers. 2011 Jan 5;15(2):361–372. doi: 10.1007/s11030-010-9297-7

Fig. 8.

Fig. 8

Activation of GABAA receptors by kushenol I, (–)-kurarinone, sophoraflavanone G, and kuraridine. a Bar graphs illustrate the amplitudes of chloride currents induced in the absence of GABA by saturating concentrations of kushenol I (1.0 ± 0.2%, n = 3, (–)-kurarinone (3.7 ± 1.1%, n = 3) sophoraflavanone G (2.1 ± 0.4%, n = 3) and kuraridine 5.0 ± 2.2%, n = 3). 100% correspond to the maximal IGABA induced by a saturating concentration (1 mM) of GABA. b Representative currents illustrating direct activation of GABAA receptors (α1β2γ2S) by kushenol I, (–)-kurarinone, sophoraflavanone G, and kuraridine in comparison to IGABA induced by 1 μM GABA