Virus	Family	No. isolates	No. locations	No. years detected	Human disease	Refs.
West Nile virus	Flaviviridae	1,002	94	12	Moderate to severe, fever, encephalitis	2,5
Eastern equine encephalitis virus	Togaviridae	292	41	10	Severe, encephalitis	6,7
Highlands J virus	Togaviridae	178	39	11	Not known	6
Jamestown Canyon virus	Bunyaviridae	305	74	14	Mild to moderate, fever, meningitis	8
Potosi virus	Bunyaviridae	259	76	4	Not known	3
Cache Valley virus	Bunyaviridae	114	51	8	Mild to severe, fever, neurological illness in two documented cases
Trivittatus virus	Bunyaviridae	83	21	11	Not known
La Crosse virus	Bunyaviridae	1	1	1	Moderate to severe, encephalitis	4
Flanders virus	Rhabdoviridae	4	4	2	Not known