FIG. 1.

Concentrations of propranolol in the treated ipsilateral periocular tissues (a) eyelids (e.g., upper eyelid inner layers, upper eyelid outer layers, lower eyelid inner layers, and lower eyelid outer layers) and (b) extraocular muscles (superior muscles, inferior muscles, and lateral and medial muscles), bulbar conjunctiva, and periocular fat, after topical instillation of 1.5 mg propranolol. Drug concentrations in plasma after topical instillation are presented for comparison. Data represent the mean and standard deviation (mean±SD, n=3 −4).