Skip to main content
. 2011 May;7(2):51–58. doi: 10.2174/157340311797484240

Table 1.

Common Underlying Diagnoses by Age in Patients Requiring Heart Transplant

Age Diagnosis Further Details

< 1 month (infancy) Hypoplastic left heart with abnormalities precluding Norwood procedure Impaired ventricular function and inlet valve regurgitation
Severe Ebstein’s anomaly Symptomatic infants
Pulmonary atresia with intact ventricular septum and abnormal coronary anatomy Right ventricular dependent coronary circulation
Severe valve abnormalities eg mitral regurgitation with impaired function.
Heterotaxy lesions Impaired ventricular function and inlet valve regurgitationf

>6 months Single ventricle At various stages of palliation eg Blalock shunt (infants), Glenn shunt (young child), Fontan (older child)
Transposition of great arteries Typically post Mustard or Senning
Right ventricular outflow tract lesions eg post op. repair with impairment of ventricular function
Ventricular/atrial septal defect eg post op. repair with impairment of ventricular function
Left ventricular outflow tract lesions eg post op. repair with impairment of ventricular function
Congenitally corrected-transposition of the great arteries eg post op. repair with impairment of ventricular function. Sometimes post double switch operation
Complete atrioventricular septal defects eg post op. repair with impairment of ventricular function and severe valve regurgitation