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. 2011 Oct 17;6(10):e24784. doi: 10.1371/journal.pone.0024784

Figure 2. Expression of EC adhesion receptors after overnight co-culture with parasite lines: Pfsbp knockout, C24, A4 and ItG and normal RBC.

Figure 2

The adhesion molecules on three EC types were measured by FACS. Data were presented as the mean percentage of response induced by EC alone ± S.D (n = 3). The increase in ICAM-1 levels in three EC types after co-cultured with parasite lines C24, A4 and ItG were extremely significant compared to co-culture with no-parasite or normal RBC (p<0.0001). The increase is also very significant compared with the level induced by the Pfsbp knockout line (p<0.001). The increase in VCAM-1 after co-culture with C24, A4 and ItG lines compared to no-parasite, RBC and Pfsbp knockout line was extremely significant in HUVEC only (p<0.0001).