Table 1.
Subject characteristics by treatment arm.
| Characteristic | Bupropion (n=274) | Placebo (n=266) | P value1 |
|---|---|---|---|
| Sex: female | 158 (57.7%) | 148 (55.6%) | 0.6349 |
| Race: white | 226 (82.5%) | 198 (74.4%) | 0.0228 |
| FTND score: ≥6 | 114 (41.6%) | 125 (47.0%) | 0.2077 |
| CESD scale: ≥16 | 90 (32.9%) | 70 (26.3%) | 0.0966 |
| Subjects quit on TQD | 200 (73.0%) | 154 (57.9%) | 0.0002 |
| Fraction of smoking days in treatment | 0.35 (SE 0.024) | 0.54 (SE 0.026) | <0.0001 |
| Self reported EOT quit | 139 (51.1%) | 91 (34.7%) | 0.0001 |
| Verified EOT quit | 94 (34.3%) | 56 (21.1%) | 0.0006 |
Note:
1
P value is for comparing the bupropion and placebo arms. It is based on t test for the continuous variable fraction of smoking days, and on the chi-squared test for all other variables, which are binary.