Fig. 2.

Silencing expression of mx or imp protects Aag2 cells from apoptotic stimuli. Aag2 cells were treated with the indicated dsRNAs for 24 h, and then 50 ng ml⁻¹ of Act D (a) or 5 μg ml⁻¹ of Aeiap1 dsRNA (b) were added. Twelve hours later, cell viability was determined by MTT assay. Data are shown as mean ± SEM of three independent experiments (***P < 0.0001; **P < 0.001 by Student’s t test)