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. Author manuscript; available in PMC: 2011 Oct 19.
Published in final edited form as: Eur J Neurosci. 2010 Jun 28;32(1):80–88. doi: 10.1111/j.1460-9568.2010.07262.x

Fig. 5.

Fig. 5

Dantrolene prevents the development of SREDs 24 and 48 h after SE but does not inhibit SREDs acutely. Representative current-clamp trace from control neuron (A), low Mg2+ -treated neuron displaying characteristic SREDs (B), and neurons treated with low Mg2+ then dantrolene (50 µm) at both 24 h (C) and 48 h (D) after treatment and were devoid of SREDs. Dantrolene did not inhibit SRED activity when added acutely to neurons displaying SREDs (n = 12–15 culture plates with a minimum of threee neurons recorded from each plate).