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Follow-up of 2 patients with metastasis after NSS
| Patient # | 1 | 2 |
| Hereditary Classification | VHL | VHL |
| Time until mets after NSS (mo) | 6 | 4 |
| Largest tumor size (cm) | 4.5 | 5.8 |
| Pathologic type | clear cell | clear cell |
| Nuclear Grade | 3 | 2 |
| Localization of metastasis | lung, scalp, retroperitoneum | lung (3 Mets) |
| Treatment | TKI | Metastatectomy for all 3 lesions |
| Follow up time (mo) | 41 | 60 |
| Outcome | Death due to cancer progression | Alive, no evidence of metastatic disease |
